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Normalize. Unify. Make It Usable.
Healthcare data is fragmented across dozens of systems and formats — EHRs, faxed PDFs, scanned images, CCDAs, HL7 messages, and free-text notes. The Data Layer ingests it all, de-duplicates patient records, converts every format, and outputs clean, standardized FHIR R4 resources. This is the foundation that makes clinical intelligence possible.
Multi-Format Ingestion
Ingest CCDAs, faxed PDFs, scanned images, XML, HL7v2, and free-text clinical notes. Every document becomes structured, queryable data — regardless of how it arrived.
FHIR R4 Normalization
Every data source is converted into clean, standardized FHIR R4 resources. Patient records are de-duplicated and reconciled across systems into a single authoritative view.
Cross-System Connectivity
Connect to EHRs via FHIR APIs, health exchanges via CommonWell and TEFCA, patient-generated data from wearables and apps, and public research corpora including PubMed and clinical trials.
WHAT THIS LAYER DELIVERS:
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Clean FHIR R4 API for any downstream application
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Patient record de-duplication and identity matching
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Universal document parsing (PDF, CCDA, XML, HL7, images)
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Cross-system data reconciliation and provenance tracking
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Real-time HIE feeds from CommonWell and TEFCA
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Intelligent clinical data normalization with RxNorm, LOINC, SNOMED-CT, and ICD-10 standardization for query-ready structured data
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Patient-generated data ingestion (wearables, RPM devices)
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Complete audit trail and data lineage for compliance
BUILT FOR:
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Health Data Integrators
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HIE Organizations
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Health Systems with Interoperability Challenges
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EHR Vendors Seeking Clean FHIR Data
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Research Institutions
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Public Health Agencies
If you’re spending months normalizing healthcare data from disparate sources, we’ve already solved it. ThetaRho’s Data Layer gives you clean, unified FHIR data — so you can focus on building what comes next.
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Understand. Reason. Enable.
Clean data alone isn’t intelligence. The AI Layer transforms normalized FHIR data into queryable clinical knowledge by adding medical ontologies, semantic embeddings, and clinical NLP. This is the layer that understands what a “medication change” means, why a lab result is clinically significant, and how a research finding applies to a specific patient. It enables any application — yours or ours — to query health data in natural language.
Semantic Search
BioClinical BERT-powered search that understands clinical intent — not just keywords. A query for ”blood pressure medications“ returns ACE inhibitors, ARBs, and calcium channel blockers, even if those exact words never appear in the record.
Medical Ontology Mapping
Every FHIR resource is annotated with standard medical ontologies — RxNorm for medications, SNOMED CT for diagnoses, LOINC for lab results, MeSH for research concepts — enabling precise clinical reasoning across systems.
Clinical QA
LLM-powered clinical question answering using Llama, Aloe, and GPT models — grounded in patient data with traceable citations. Every response is verifiable. Every source is linked. Nothing is hallucinated.
WHAT THIS LAYER DELIVERS:
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Natural language query API over patient data
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Semantic search with clinical intent understanding
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Medical ontology annotation (RxNorm, SNOMED, LOINC, MeSH)
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Clinical embedding generation for downstream ML models
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Grounded AI responses with full source traceability
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Agentic workflow orchestration engine
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Patient-context matching against research corpora
BUILT FOR:
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Health Tech Application Developers
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Clinical AI Startups
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EHR Vendor Adding AI Capabilities
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Life Sciences & Pharma (Real-World Evidence)
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Population Health Platforms
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Clinical Research Organizations
Building a clinical application? Don’t build your own NLP pipeline, ontology mapper, or grounding engine. ThetaRho’s AI Layer gives you natural language access to clinically annotated, grounded health data — through a single API.
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Intelligence Meets Workflow.
This is where clinical intelligence becomes clinical action. The App Layer delivers production-ready applications — starting with RISA — that physicians use inside their EHR every day. Chart review, patient-contextualized research, clinical decision support, and agentic task execution. Every application is powered by the Data and AI layers below, so it works with the full patient picture from day one.
RISA—Clinical Intelligence
Four kinds of clinical intelligence in one application: Retrieve patient data, Investigate clinical questions with contextualized research, Synthesize insights across sources, and Act through AI agents. Live inside athenaOne today.
Agentic Clinical Actions
AI agents that execute tasks on behalf of physicians — preparing orders, drafting referral summaries, generating prior authorization justifications, and producing billing recommendations. Always with physician review and approval.
Custom Workflow Builder
Build your own clinical applications on top of ThetaRho’s Data and AI layers. Access the same infrastructure that powers RISA — through APIs designed for health tech developers and health systems.
PLATFORM APPLICATIONS — CURRENT & ROADMAP
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RISA Chart Review — Live
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Clinical Documentation — Live
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Agentic Clinical Actions (Orders, Referrals) — Next
- Patient-Contextualized Research — Live
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Clinical Decision Support — Future
BUILT FOR:
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Health Tech Application Developers
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Clinical AI Startups
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EHR Vendor Adding AI Capabilities
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Life Sciences & Pharma (Real-World Evidence)
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Population Health Platforms
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Clinical Research Organizations
Production-proven. Ready to build on.
ThetaRho's platform powers RISA — a certified athenahealth Marketplace application live at multiple clinics today. Whether you need clean FHIR data, AI-powered clinical reasoning, or a proven application framework — let's talk.
